S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.
Författare
Summary, in English
Breast cancer is the most common cancer form among women today. Depending on hormone receptor status, breast cancers are divided into different subtypes with vastly varying prognosis. S100A9 is a calcium-binding protein that is associated with inflammation and expressed not only in myeloid cells but also in some tumours. The role for S100A9 in the malignant cells is not well characterised; however, previous studies have shown that the protein could have important immune-modulating properties.
Avdelning/ar
- Experimentell infektionsmedicin, Malmö
- Tumörmikromiljö
- Cancerimmunologi, Malmö
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- Immunology
Publiceringsår
2015
Språk
Engelska
Sidor
1234-1243
Publikation/Tidskrift/Serie
British Journal of Cancer
Volym
113
Issue
8
Fulltext
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Nature Publishing Group
Ämne
- Cancer and Oncology
Status
Published
Forskningsgrupp
- Experimental Infection Medicine, Malmö
- Cancer Immunology, Malmö
- Immunology
ISBN/ISSN/Övrigt
- ISSN: 1532-1827