Changes in the pattern of paracetamol use in the periconception period in a Danish cohort
Författare
Summary, in English
Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web-based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking, co-morbidities, body mass index 25kg/m(2), unplanned pregnancy, no education and inability to understand Danish. A significant decrease in the proportion of women with any paracetamol use in early pregnancy was noted after access to large packs was restricted by legislation.
Avdelning/ar
Publiceringsår
2015
Språk
Engelska
Sidor
898-903
Publikation/Tidskrift/Serie
Acta Obstetricia et Gynecologica Scandinavica
Volym
94
Issue
8
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley-Blackwell
Ämne
- Obstetrics, Gynecology and Reproductive Medicine
Nyckelord
- Paracetamol
- acetaminophen
- pregnancy
- antenatal care
- prenatal care
- exposure
Status
Published
Projekt
- Children with cancer
Forskningsgrupp
- Child and Family Health
ISBN/ISSN/Övrigt
- ISSN: 1600-0412