Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Identification of a novel protease inhibitor gene that is highly expressed in the prostate.

In English

Författare

Summary, in English

A novel gene was identified 52 kb upstream of the gene encoding the protease inhibitor elafin (PI3) on human chromosome 20q12-13.1. The transcript of the new gene, denoted huWAP2, was characterized by rapid amplification of cDNA ends and DNA sequencing. The size is 774 bp and it gives rise to a polypeptide of 111 amino acid residues that is homologous to elafin and similar WAP-type protease inhibitors. By RT-PCR it was shown that the gene is highly expressed in prostate, skin, lung, and esophagus.

Publiceringsår

2002

Språk

Engelska

Sidor

452-456

Publikation/Tidskrift/Serie

Biochemical and Biophysical Research Communications

Volym

290

Issue

1

Dokumenttyp

Artikel i tidskrift

Förlag

Elsevier

Ämne

  • Biological Sciences

Nyckelord

  • Male
  • Molecular Sequence Data
  • Prostate : metabolism
  • Protease Inhibitors : chemistry
  • Protein Structure Tertiary
  • Reverse Transcriptase Polymerase Chain Reaction
  • Proteins : biosynthesis : chemistry : genetics
  • Sequence Analysis DNA
  • Sequence Homology Amino Acid
  • Sequence Homology Nucleic Acid
  • Tissue Distribution
  • Support Non-U.S. Gov't
  • Exons
  • Human
  • DNA Complementary : metabolism
  • Chromosomes Human Pair 20
  • Base Sequence
  • Amino Acid Sequence

Status

Published

Forskningsgrupp

  • Clinical Chemistry, Malmö

ISBN/ISSN/Övrigt

  • ISSN: 1090-2104