Use of ciprofloxacin in patients undergoing transurethral prostatic surgery
Författare
Summary, in English
The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection and compared with that of controls without antibiotic (Group III). Both regimens significantly reduced the frequency of post-operative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) compared to the controls. Both regimens were equally effective in preventing peri-operative and post-operative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found post-operatively in 35% in Group I and in 9% in Group II (p = 0.012), but in 82% of the patients in Group III. Ciprofloxacin inhibited all but 7 of 176 bacterial strains at an MIC of less than or equal to 1 microgram/ml. Given orally, ciprofloxacin is a valuable alternative antimicrobial for use in conjunction with transurethral prostatic resection. A short course is sufficient for prophylaxis, and adequate therapy is achieved with a prolonged regimen.
Avdelning/ar
Publiceringsår
1989
Språk
Engelska
Sidor
104-107
Publikation/Tidskrift/Serie
Scandinavian Journal of Infectious Diseases. Supplementum
Volym
60
Dokumenttyp
Artikel i tidskrift
Förlag
Scandinavian University Press
Ämne
- Clinical Medicine
- Microbiology in the medical area
- Cancer and Oncology
- Urology and Nephrology
Status
Published
Forskningsgrupp
- Clinical Microbiology, Malmö
- Urological cancer, Malmö
ISBN/ISSN/Övrigt
- ISSN: 0300-8878