Spasmolytic flavonols from Artemisia abrotanum
Författare
Summary, in English
Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.
Publiceringsår
1995
Språk
Engelska
Sidor
370-371
Publikation/Tidskrift/Serie
Planta Medica
Volym
61
Issue
4
Dokumenttyp
Artikel i tidskrift
Förlag
Georg Thieme Verlag
Ämne
- Dermatology and Venereal Diseases
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0032-0943