The mouse trap

Summary, in English

Mouse models of asthma are now being used extensively in drug research. However, the successful unravelling of combinatorial interplays of cells and molecules in the murine airways may not be matched by equally successful demonstrations of an asthma-like pathophysiology. Here, Carl Persson, Jonas Erjefalt, Magnus Korsgren and Frank Sundler discuss the fact that major features of asthma may still need to be demonstrated in the airways of allergic mice.

• Författare: Carl Persson; Jonas Erjefält; Magnus Korsgren; Frank Sundler
• Avdelning/ar: Avdelningen för klinisk kemi och farmakologi; Luftvägsinflammation; Institutionen för experimentell medicinsk vetenskap
• Publiceringsår: 1997
• Språk: Engelska
• Sidor: 465-467
• Publikation/Tidskrift/Serie: Trends in Pharmacological Sciences
• Volym: 18
• Issue: 12
• Länkar: http://dx.doi.org/10.1016/S0165-6147(97)01142-5
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Cell and Molecular Biology; Immunology in the medical area; Medicinal Chemistry; Pharmacology and Toxicology
• Nyckelord: mucosal pathophysiology; epithelial changes; leukocytes; airways disease; eosinophils; allergy; asthma; mouse model
• Status: Published
• Forskningsgrupp: Airway Inflammation and Immunology
• ISBN/ISSN/Övrigt: ISSN: 0165-6147