Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Lactoferrin and Cancer Disease Prevention

In English

Författare

  • Ligia Rodrigues
  • Jose Teixeira
  • Fernando Schmitt
  • Marie Paulsson
  • Helena Lindmark Månsson

Summary, in English

Lactoferrin (LF) is an iron-binding glycoprotein that is composed of the transferrin family and is predominantly found in the products of the exocrine glands located in the gateways of the digestive, respiratory, and reproductive systems, suggesting a role in the non-specific defence against invading pathogens. Additionally, several physiological roles have been attributed to LF, namely regulation of iron homeostasis, host defence against infection and inflammation, regulation of cellular growth, and differentiation and protection against cancer development and metastasis. These findings have suggested LF's great potential therapeutic use in cancer disease prevention and/or treatment, namely as a chemopreventive agent. This review looks at the recent advances in understanding the mechanisms underlying the multifunctional roles of LF and future perspectives on its potential therapeutic applications.

Avdelning/ar

  • Department of Food Technology, Engineering and Nutrition

Publiceringsår

2009

Språk

Engelska

Sidor

203-217

Publikation/Tidskrift/Serie

Critical Reviews in Food Science and Nutrition

Volym

49

Issue

3

Dokumenttyp

Artikel i tidskrift

Förlag

Taylor & Francis

Ämne

  • Food Engineering

Nyckelord

  • infection
  • lactoferrin
  • chemoprevention
  • inflammation
  • cancer

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1040-8398