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Allelic polymorphism in MHC class IIB in four populations of Atlantic salmon (Salmo salar)

Publiceringsår: 2001
Språk: Engelska
Sidor: 329-336
Publikation/Tidskrift/Serie: Immunogenetics
Volym: 53
Nummer: 4
Dokumenttyp: Artikel
Förlag: Springer-Verlag GmbH

Sammanfattning

We sequenced exon 2 of the MHC class II B gene in Atlantic salmon from the Baltic Sea and identified 17 different exon 2 alleles among 22 different restriction fragment length polymorphism haplotypes. The sequences differed at between I and 34 bases. Two different tests were used to estimate the importance of recombination in the generation of new alleles. Recombination events appear to have occurred between three and nine times. Only two pairs of sequences differed by less than five nucleotides', minimizing the importance of point mutations for generating new alleles. Phylogenetic analysis showed that sequences did not cluster according to populations, and genetic distances between populations were small compared to those obtained by allele frequency data. These results, together with the similarity found between exon 2 sequences from Baltic salmon and Norwegian salmon, indicate that all of the identified alleles were present in the ancient salmon population colonizing the Baltic rivers after the last glaciation.

Disputation

Nyckelord

  • Biology and Life Sciences

Övrigt

Published
Yes
  • Molecular Ecology and Evolution Lab
  • ISSN: 0093-7711
  • ISSN: 1432-1211

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