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Life-time adversities, reported thirteen years after a suicide attempt: relationship to recovery, 5HTTLPR genotype, and past and present morbidity.

Publiceringsår: 2009
Språk: Engelska
Sidor: 214-229
Publikation/Tidskrift/Serie: Archives of Suicide Research
Volym: 13
Nummer: 3
Dokumenttyp: Artikel
Förlag: Routledge, Taylor & Francis Group

Sammanfattning

In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported by suicide attempters than controls, and by still-ill than recovered suicide attempters. Adversities reported at follow-up were related to psychiatric morbidity at follow-up, but not to morbidity 13 years earlier. The 5-HTTLPR, genotype was associated with reported adversities, but not chances of recovery. Adversities potentially affected chronic morbidity. 5-HTTLPR genotype did not affect long-term recovery.

Disputation

Nyckelord

  • Medicine and Health Sciences
  • Social Sciences
  • outcome
  • life-events
  • follow-up
  • gene
  • self-harm
  • suicide

Övriga

Published
Yes
  • ISSN: 1381-1118

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