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Attovial-based antibody nanoarrays.

Författare:
Publiceringsår: 2009
Språk: Engelska
Sidor: 5406-5413
Publikation/Tidskrift/Serie: Proteomics
Volym: 9
Nummer: 24
Dokumenttyp: Artikel
Förlag: WILEY-VCH Verlag GmbH & Co

Sammanfattning

Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human serum samples. Finally, we demonstrated proof-of-concept for individual functionalisation of the attovials with a recombinant antibody.

Disputation

Nyckelord

  • Biology and Life Sciences
  • Technology and Engineering

Övriga

Published
Yes
  • ISSN: 1615-9861

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