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Variation in the innate and acquired arms of the immune system among five shorebird species

Författare:
Publiceringsår: 2006
Språk: Engelska
Sidor: 284-291
Publikation/Tidskrift/Serie: Journal of Experimental Biology
Volym: 209
Nummer: 2
Dokumenttyp: Artikel
Förlag: THE COMPANY OF BIOLOGISTS LTD

Sammanfattning

To contribute to an understanding of the evolutionary processes that shape variation in immune responses, we compared several components of the innate and acquired arms of the immune system in five related, but ecologically diverse, migratory shorebirds (ruff Philomachus pugnax L., ruddy turnstone Arenaria interpres L., bar-tailed godwit Limosa lapponica L., sanderling Calidris alba Pallas and red knot C. canutus L.). We used a hemolysis-hemagglutination assay in free-living shorebirds to assess two of the innate components (natural antibodies and complement-mediated lysis), and a modified quantitative enzyme-linked immunosorbent assay in birds held in captivity to assess the acquired component (humoral antibodies against tetanus and diphtheria toxoid) of immunity. Ruddy turnstones showed the highest levels of both innate and acquired immune responses. We suggest that turnstones could have evolved strong immune responses because they scavenge among rotting organic material on the seashore, where they might be exposed to a particularly broad range of pathogens. Although ruffs stand out among shorebirds in having a high prevalence of avian malaria, they do not exhibit higher immune response levels. Our results indicate that relationships between immune response and infection are not likely to follow a broad general pattern, but instead depend on type of parasite exposure, among other factors.

Disputation

Nyckelord

  • Biology and Life Sciences

Övriga

Published
  • Molecular Ecology and Evolution Lab
  • ISSN: 0022-0949
  • ISSN: 1477-9145

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