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Genomics and the irreducible nature of eukaryote cells

Författare:
Publiceringsår: 2006
Språk: Engelska
Sidor: 1011-1014
Publikation/Tidskrift/Serie: Science
Volym: 312
Nummer: 5776
Dokumenttyp: Artikel
Förlag: AAAS American association for the advancement of science

Sammanfattning

Large-scale comparative genomics in harness with proteomics has substantiated fundamental features of eukaryote cellular evolution. The evolutionary trajectory of modern eukaryotes is distinct from that of prokaryotes. Data from many sources give no direct evidence that eukaryotes evolved by genome fusion between archaea and bacteria. Comparative genomics shows that, under certain ecological settings, sequence loss and cellular simplification are common modes of evolution. Subcellular architecture of eukaryote cells is in part a physical-chemical consequence of molecular crowding; subcellular compartmentation with specialized proteomes is required for the efficient functioning of proteins.

Disputation

Nyckelord

  • Biology and Life Sciences

Övriga

Published
Yes
  • Microbial Ecology
  • ISSN: 0036-8075

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