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Open partial nephrectomy for renal cell cancer in a medium patient volume centre: Is high quality possible?

In English

Författare

Summary, in English

Abstract Objective. To describe the surgical complication rate of open partial nephrectomy (OPN) in patients with renal tumours, and to report the oncological long-term outcome in unilateral renal cell cancer patients subjected to this procedure, from a medium patient volume urological centre. Material and methods. Data from all patients (n = 89) subjected to OPN for proven or suspected renal cell cancer during the period 1965-2007 were registered in a specifically designed database system. Tumour stage and size, surgical margin, histology, perioperative and postoperative complications were analysed in all patients. In addition, long-term follow-up outcomes in malignant unilateral tumours (n = 51) were analysed. Results. Seventy-four of the resected tumours were malignant. Six of these had a positive surgical margin; five from patients with multifocal or bilateral tumours and one from a patient with a solitary malignant cyst. Perioperative complications were registered in only one case (1%). Postoperative complications (within 30 days postoperatively) reached 18%. The long-term follow-up (mean 79 months, median 49 months, range 14 months to 26 years) in patients with unilateral malignant tumours, all staged T1-T2, revealed two systemic recurrences, both in patients with poor prognostic markers at the time of surgery, but no local recurrence. Conclusions. OPN has complication rates similar to open radical nephrectomy. Long-term tumour control in unilateral cases and with organ confined disease is excellent. The results demonstrate that carefully performed OPN at a medium-volume centre can achieve equal results to high-volume centres.

Avdelning/ar

Publiceringsår

2010

Språk

Engelska

Sidor

204-211

Publikation/Tidskrift/Serie

Scandinavian Journal of Urology and Nephrology

Volym

44

Dokumenttyp

Artikel i tidskrift

Förlag

Taylor & Francis

Ämne

  • Urology and Nephrology

Status

Published

Forskningsgrupp

  • Urology

ISBN/ISSN/Övrigt

  • ISSN: 1651-2065