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Crossed over repair of the femoral sensory and motor branches influences N-CAM

In English

Författare

Summary, in English

N-CAM, expressed by non-myelinating Schwann cells, was investigated by immunohistochemistry in transected rat femoral nerves, which were repaired either using a straight or a crossed over technique. N-CAM staining covered 30 and 11% of the cross-sectional area of and motor branches, respectively, in uninjured nerves. After 3 days there was a transient smaller area of N-CAM staining following both the repairs. After a straight repair N-CAM area increased to the control values in both branches. In contrast, a crossed over repair resulted in a continuous increase of N-CAM in the motor branch, whereas the area in the sensory branch returned slowly to control values. N-CAM is influenced by an intentionally misdirected outgrowth of motor and sensory axons after nerve repair. NeuroReport 21:841-845 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.

Publiceringsår

2010

Språk

Engelska

Sidor

841-845

Publikation/Tidskrift/Serie

NeuroReport

Volym

21

Issue

12

Dokumenttyp

Artikel i tidskrift

Förlag

Lippincott Williams & Wilkins

Ämne

  • Neurosciences

Nyckelord

  • neurofilaments
  • nerve repair
  • nerve regeneration
  • N-CAM
  • axons
  • misdirection
  • non-myelinating
  • Schwann cells

Status

Published

Forskningsgrupp

  • Hand Surgery, Malmö

ISBN/ISSN/Övrigt

  • ISSN: 1473-558X