Standardizing plasma protein measurements worldwide: a challenging enterprise
Författare
Summary, in English
The need for harmonizing laboratory results is particularly intense in the field of quantitative protein assays in consideration of the clinical impact of specific protein measurements and their relevance in monitoring disease. We report the efforts made by the Committee on Plasma Proteins of the IFCC Scientific Division to achieve worldwide comparability in plasma protein results. We focus on the production of reference materials and the methods applied throughout their production process. Particularly, the recent characterization of ERM-DA470k/IFCC and ERM-DA472/IFCC has demonstrated that it is possible to reproduce the earlier established procedures and thereby maintain standardization. Plasma protein reference materials have had a substantial impact in improving the harmonization of patient protein results that should translate into better patient care. Clin Chem Lab Med 2010;48:1567-75.
Avdelning/ar
Publiceringsår
2010
Språk
Engelska
Sidor
1567-1575
Publikation/Tidskrift/Serie
Clinical Chemistry and Laboratory Medicine
Volym
48
Issue
11
Dokumenttyp
Artikel i tidskrift
Förlag
De Gruyter
Ämne
- Clinical Laboratory Medicine
Nyckelord
- reference material
- harmonization
- plasma proteins
- traceability
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1434-6621