Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly

Summary, in English

Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction.

• Författare: Björn Hultberg; Anders Isaksson; Karin Nilsson; Lars Gustafson
• Avdelning/ar: Avdelningen för klinisk kemi och farmakologi; Psykiatri, Lund
• Publiceringsår: 2001
• Språk: Engelska
• Sidor: 873-878
• Publikation/Tidskrift/Serie: International Journal of Geriatric Psychiatry
• Volym: 16
• Issue: 9
• Länkar: http://dx.doi.org/10.1002/gps.439
• Dokumenttyp: Artikel i tidskrift
• Förlag: John Wiley & Sons Inc.
• Ämne: Geriatrics; Psychiatry
• Nyckelord: blood; cobalamin; folate; homocysteine; methylmalonic acid; plasma; psychogeriatric patients
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1099-1166