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Mouse monoclonal antibodies with anti-A, anti-B and anti-A,B specificities; some superior to human polyclonal ABO reagents

In English

Författare

  • L Messeter
  • T Brodin
  • Alan Chester
  • B Low
  • A Lundblad

Summary, in English

A series of fusions using mouse myeloma cells and spleen cells from mice immunized with blood group substances or human red cells was performed with the aim of obtaining ABO antibodies suitable for routine blood grouping. Seven strongly agglutinating antibodies against antigens in the ABO system were obtained from 18 fusions. These antibodies were tested extensively in manual and automated routines, and six of them were found to be as good as or better than commercial polyclonal test sera of human origin.

Publiceringsår

1984

Språk

Engelska

Sidor

185-194

Publikation/Tidskrift/Serie

Vox Sanguinis

Volym

46

Issue

4

Dokumenttyp

Artikel i tidskrift

Förlag

Wiley-Blackwell

Ämne

  • Hematology

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1423-0410