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Relation Between Growth And Bone Collagen Content In Young Pigs; Effects Of Dietary Alpha-Ketoglutarate Supplementation

Författare:
Publiceringsår: 2011
Språk: Engelska
Sidor: 287-292
Publikation/Tidskrift/Serie: Bulletin of the Veterinary Institute in Pulawy
Volym: 55
Nummer: 2
Dokumenttyp: Artikel
Förlag: Natl Veterinary Research Inst

Sammanfattning

The aim of this study was to determine the effect of dietary supplementation with alpha-ketoglutarate (AKG) sodium salt on growth rate in relation to bone collagen formation during the first 70 d of postnatal life in piglets. The results show that dietary AKG supplementation increased body weight of the experimental piglets in comparison to the controls, especially between 21(st) and 56(th) d of life (P <= 0.01). Moreover, the area of collagen trabeculae slightly increased in experimental age sub-groups and reached the highest differences between 14(th) (P <= 0.01) and 70(th) d of piglets life (P <= 0.001). In contrast, the highest values for the number of collagen trabeculae were observed in piglets at 3(rd) d of age, regardless of treatment group. The positive effect of AKG supplementation on the number of collagen trabeculae was found between 3(rd) and 35(th) d of life, with statistical confirmation at days 14, 35, and 56 (P <= 0.01). The data-lines of the bone strain showed similar course during the whole experimental period, except 56(th) d of life, when the experimental piglets reached statistically significant, higher values in comparison to the controls (P <= 0.05). Similarly, the blood plasma osteocalcin reached the highest concentration in experimental sub-groups from 21(st) d of life in comparison to the controls, with statistical significance at the age of 56 (P <= 0.05). These data indicate that dietary AKG supplementation effectively stimulated collagen synthesis in young growing piglets, both before and after weaning.

Disputation

Nyckelord

  • Biology and Life Sciences
  • piglets
  • bone
  • collagen
  • alpha-ketoglutarate

Övriga

Published
Yes
  • ISSN: 0042-4870

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