Differences in serum levels of CB-153 and p,p '-DDE, and reproductive parameters between men living south and north in Norway
Författare
Summary, in English
Arctic is contaminated with persistent organochlorine pollutants (POPs), and exposure to these compounds may differ between south and north in Norway. POPs may have negative impact on male reproductive characteristics. We compared serum levels of the CB-153 and p,p'-DDE in men who were born and had lived most of their lifetime south and north (close to or above the Arctic Circle) in Norway. We found no geographical differences in levels of CB-153 (south: 50 ng/g lipid (mean), north: 59 ng/g lipid; p = 0.27) or sperm parameters. However, the levels of AV-ODE were higher in south than in north (81 ng/g lipid (mean) vs. 66 ng/g lipid; p = 0.02), as were the levels of total and free testosterone. The FSH levels were lowest in south. A strong relationship between the CB-153 and the SHBG levels was observed. The regional differences observed for p,p'-DDE, testosterone and FSH were not reflected in the semen quality. (C) 2011 Elsevier Inc. All rights reserved.
Publiceringsår
2011
Språk
Engelska
Sidor
261-267
Publikation/Tidskrift/Serie
Reproductive Toxicology
Volym
32
Issue
3
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Obstetrics, Gynecology and Reproductive Medicine
Nyckelord
- Reproductive hormones
- Sperm characteristics
- POPs
- CB-153
- p '-DDE
- p
- Norway
- Geographical difference
- Male
Status
Published
Forskningsgrupp
- Reproductive medicine, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1873-1708