Synthesis of Formylsilanes through Oxidative Cleavage of α-Silyl Glycols.

Summary, in English

A convenient method for the synthesis and isolation of highly reactive formylsilanes by oxidative cleavage of α-silyl glycols is presented. The mild conditions provide an entry to acid- and heat-sensitive members of this theoretically intriguing class of compounds. The utility of the method is demonstrated through the isolation and subsequent diastereoselective derivatization of t-BuMe2- and t-BuPh2-formylsilanes, previously not reported in isolated form.

• Författare: Henrik von Wachenfeldt; Daniel Strand
• Avdelning/ar: Centrum för analys och syntes
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 12268-12273
• Publikation/Tidskrift/Serie: Journal of Organic Chemistry
• Volym: 78
• Issue: 23
• Länkar: http://dx.doi.org/10.1021/jo402123j
• Dokumenttyp: Artikel i tidskrift
• Förlag: The American Chemical Society (ACS)
• Ämne: Chemical Sciences
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1520-6904