Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.

Summary, in English

Despite the extensive use of retinal photocoagulation for ischaemia and vascular leakage in retinal vascular disease, the molecular mechanisms behind its clinical beneficial effects are still poorly understood. One important target of laser irradiation is the retinal pigment epithelium (RPE). In this study, we aimed at identifying the isolated effects of photocoagulation of RPE at both the mRNA and protein expression levels.

• Författare: Poya T-Khani; Carolina de la Torre; Francesc Canals; Hedvig Bennet; Rafael Simo; Cristina Hernandez; Malin Fex; Carl-David Agardh; Ola Hansson; Elisabet Agardh
• Avdelning/ar: Oftalmologi (Malmö); Celiaki och diabetes; Institutionen för kliniska vetenskaper, Malmö; EXODIAB: Excellence of Diabetes Research in Sweden
• Publiceringsår: 2015
• Språk: Engelska
• Sidor: 348-354
• Publikation/Tidskrift/Serie: Acta Ophthalmologica
• Volym: 93
• Issue: 4
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/25604382?dopt=Abstract; http://dx.doi.org/10.1111/aos.12649
• Dokumenttyp: Artikel i tidskrift
• Förlag: Wiley-Blackwell
• Ämne: Ophthalmology
• Status: Published
• Forskningsgrupp: Ophthalmology (Malmö); Celiac Disease and Diabetes Unit
• ISBN/ISSN/Övrigt: ISSN: 1755-3768