Skeletal muscle atrophy in r6/2 mice - altered circulating skeletal muscle markers and gene expression profile changes.

Summary, in English

In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology, including progressive skeletal muscle wasting, and common skeletal muscle gene expression changes have been shown in HD mice and human HD.

• Författare: Anna Magnusson-Lind; Marcus Davidsson; Edina Silajdzic; Christian Hansen; Andy McCourt; Sarah J Tabrizi; Maria Björkqvist
• Avdelning/ar: Biomarkörer vid hjärnsjukdomar; Molecular Neurobiology; Neural plasticitet och reparation; MultiPark: Multidisciplinary research focused on Parkinson´s disease
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 13-24
• Publikation/Tidskrift/Serie: Journal of Huntington's disease
• Volym: 3
• Issue: 1
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/25062762?dopt=Abstract; http://dx.doi.org/10.3233/JHD-130075
• Dokumenttyp: Artikel i tidskrift
• Förlag: IOS Press
• Ämne: Neurology
• Status: Published
• Forskningsgrupp: Biomarkers in Brain Disease; Molecular Neurobiology; Neural Plasticity and Repair
• ISBN/ISSN/Övrigt: ISSN: 1879-6397