Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells.
Författare
Summary, in English
Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future cell-based therapy for lung diseases. However, the cellular identity of the primary MSC in human lung tissues has not yet been reported. This study therefore aimed to identify and characterise the 'bona fide' MSC in human lungs and to investigate if the MSC numbers correlate with the development of bronchiolitis obliterans syndrome in lung-transplanted patients.
Avdelning/ar
- Lungbiologi
- Lungmedicin, allergologi och palliativ medicin
- Stamcellscentrum (SCC)
- Avdelningen för klinisk genetik
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- Institutionen för hälsovetenskaper
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
- EpiHealth: Epidemiology for Health
Publiceringsår
2014
Språk
Engelska
Publikation/Tidskrift/Serie
BMJ Open Respiratory Research
Volym
1
Issue
1
Fulltext
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BMJ Publishing Group
Ämne
- Cell and Molecular Biology
Status
Published
Forskningsgrupp
- Lung Biology
ISBN/ISSN/Övrigt
- ISSN: 2052-4439