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Sensitivity of mongolian gerbils to trichloroethylene exposure during neonatal growth

In English

Författare

Summary, in English

Continuous exposure of young mongolian gerbils to trichloroethylene (230 ppm) was started at different times during the first month of life. The onset of exposure was accompanied by an increased number of deaths among the pups and by an immediate reduction in growth rate. The proportion of dead pups was greatest when exposure was started at birth, and decreased rapidly with increasing age at onset of exposure. Growth rate was partially restored approx. 1 week after the onset of exposure. After weaning the effect of the exposure on growth decreased, and the variation in the effect among different litters was considerably reduced. The enhanced sensitivity of the pups to trichloroethylene (TCE) exposure is believed to be due to a disturbance in the mother-offspring relationship.

Publiceringsår

1982

Språk

Engelska

Sidor

97-101

Publikation/Tidskrift/Serie

Toxicology Letters

Volym

14

Issue

1-2

Dokumenttyp

Artikel i tidskrift

Förlag

Elsevier

Ämne

  • Probability Theory and Statistics

Nyckelord

  • Mongolian gerbil
  • trichloroethylene
  • Meriones unguiculatus
  • neonatal
  • growth

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1879-3169