Characterization of probe contact effects on diffuse reflectance spectroscopy measurements
Författare
Summary, in English
Diffuse reflectance spectroscopy (DRS) is a rapid, non-invasive optical method widely adopted to gain diagnostic information of tissue. The most flexible approach to this method is a fiber-optic contact-probe used with a spectroscopy system. A challenge of this method is that the external pressure brought by the probe can significantly affect the tissue optical properties as well as the light coupling into the probe, and thus influence the collected DRS-spectrum. In this study we investigate and characterize the effect of probe pressure on DRS-spectra obtained with a calibrated loaded-spring system used with a fiber optic probe in the range (400 – 1600) nm. A multilayer FE-model of the indentation is developed to get a better insight of the distribution of pressure and stresses inside the skin under indentation.
Publiceringsår
2015
Språk
Engelska
Sidor
953143-953143
Publikation/Tidskrift/Serie
BioPhotonics South America (SPIE Proceedings)
Volym
9531
Dokumenttyp
Konferensbidrag
Förlag
SPIE
Ämne
- Atom and Molecular Physics and Optics
- Applied Mechanics
Nyckelord
- Diffuse reflectance spectroscopy
- probe contact pressure
- finite element simulation
- biomechanical
- tissue optical properties.
Conference name
Joint Meeting of the 1st SPIE Conference on Biophotonics South America (BSA) / 15th World Congress of the International-Photodynamic-Association (IPA)
Conference date
2015-05-23 - 2015-05-25
Conference place
Rio de Janeiro, Brazil
Status
Published
Forskningsgrupp
- Biophotonics
ISBN/ISSN/Övrigt
- ISSN: 0277-786X
- ISSN: 1996-756X