Brain matrix: structure, turnover and necessity.

Summary, in English

Aided by mice with multiple deleted brain matrix protein genes, the biochemical analysis of mouse brain matrix molecules indicates a constitutive production of more proteoglycans than can be integrated in multimolecular matrix structures. Possible functions of non-matrix integrated proteoglycans, and aspects of incomplete compensatory mechanisms in knockout mice are discussed.

• Författare: Uwe Rauch
• Avdelning/ar: Kärlväggsbiologi
• Publiceringsår: 2007
• Språk: Engelska
• Sidor: 656-660
• Publikation/Tidskrift/Serie: Biochemical Society Transactions
• Volym: 35
• Issue: 4
• Länkar: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17635114&dopt=Abstract; http://www.biochemsoctrans.org/bst/035/bst0350656.htm
• Dokumenttyp: Artikel i tidskrift
• Förlag: Biochemical Society
• Ämne: Biochemistry and Molecular Biology
• Nyckelord: Brain matrix; structure; turnover
• Status: Published
• Forskningsgrupp: Vessel Wall Biology
• ISBN/ISSN/Övrigt: ISSN: 0300-5127