High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.
Författare
Summary, in English
The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular disease whereas the members of the cathepsin protease family are less studied.
Avdelning/ar
Publiceringsår
2016
Språk
Engelska
Sidor
000353-000353
Publikation/Tidskrift/Serie
Open Heart
Volym
3
Issue
1
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BMJ Publishing Group
Ämne
- Cardiac and Cardiovascular Systems
Status
Published
Forskningsgrupp
- Cardiovascular Research - Translational Studies
- Cardiovascular Research - Immunity and Atherosclerosis
- Cardiovascular Research - Epidemiology
ISBN/ISSN/Övrigt
- ISSN: 2053-3624