Human papilloma virus in skin, mouth and uterine cervix in female renal transplant recipients with or without a history of cutaneous squamous cell carcinoma
Författare
Summary, in English
Some human papilloma viruses are thought to be associated with skin cancer. In this pilot study, 21 female renal transplant carriers, 10 with a history of skin squamous cell carcinoma and 11 without, together with 9 age-matched healthy women were investigated for human papilloma virus DNA in sun-exposed (forehead) and less sun-exposed (buttock) skin, mouth and uterine cervix. Paraffin-embedded tumours from 9 of the patients with a history of squamous cell carcinoma were analysed. Healthy skin from both the healthy and the immunosuppressed individuals harboured a wide variety of papilloma viruses. In the healthy individuals, samples from less sun-exposed skin showed a lower prevalence of human papilloma virus DNA than corresponding samples from the immunosuppressed patients (4/9 and 7/9, respectively). Among the immunosuppressed patients, human papillomavirus DNA was found as frequently in buttock samples (17/21) as in forehead samples (17/20). There was no increased prevalence of human papillomavirus in the cervix or mouth samples from the immunosuppressed patients.
Avdelning/ar
Publiceringsår
2007
Språk
Engelska
Sidor
219-222
Publikation/Tidskrift/Serie
Acta Dermato-Venereologica
Volym
87
Issue
3
Dokumenttyp
Artikel i tidskrift
Förlag
Medical Journals Limited
Ämne
- Dermatology and Venereal Diseases
Nyckelord
- polymerase chain
- human papilloma virus
- kidney transplant patients
- squamous cell carcinoma
- reaction
Status
Published
Forskningsgrupp
- Clinical Microbiology, Malmö
- Epidemiology
ISBN/ISSN/Övrigt
- ISSN: 1651-2057