The complexity of inferring a minimally resolved phylogenetic supertree
Författare
Summary, in English
A recursive algorithm by Aho et al. [SIAM J. Comput., 10 (1981), pp. 405-421] forms the basis for many modern rooted supertree methods employed in Phylogenetics. However, as observed by Bryant [Building Trees, Hunting for Trees, and Comparing Trees: Theory and Methods in Phylogenetic Analysis, Ph.D. thesis, University of Canterbury, Christchurch, New Zealand, 1997], the tree output by the algorithm of Aho et al. is not always minimal; there may exist other trees which contain fewer nodes yet are still consistent with the input. In this paper, we prove strong polynomial-time inapproximability results for the problem of inferring a minimally resolved supertree from a given consistent set of rooted triplets (MINRS). Furthermore, we show that the decision version of MINRS is NP-hard for any fixed positive integer q >= 4, where q is the number of allowed internal nodes, but linear-time solvable for q <= 3. In contrast, MINRS becomes polynomial-time solvable for any q when restricted to caterpillars. We also present an exponential-time algorithm based on tree separators for solving MINRS exactly. It runs in 2(O(n log p)) time when every node may have at most p children that are internal nodes and where n is the cardinality of the leaf label set. Finally, we demonstrate that augmenting the algorithm of Aho et al. with an algorithm for optimal graph coloring to help merge certain blocks of leaves during the execution does not improve the output solution much in the worst case.
Avdelning/ar
- Computer Science
Publiceringsår
2012
Språk
Engelska
Sidor
272-291
Publikation/Tidskrift/Serie
SIAM Journal on Computing
Volym
41
Issue
1
Dokumenttyp
Artikel i tidskrift
Förlag
Society for Industrial and Applied Mathematics
Ämne
- Computer Science
Nyckelord
- tree separator
- graph coloring
- NP-hardness
- minimally resolved supertree
- rooted triplet
- phylogenetic tree
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0097-5397