Antisense RNAs everywhere?
Författare
Summary, in English
In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.
Publiceringsår
2002
Språk
Engelska
Sidor
223-226
Publikation/Tidskrift/Serie
Trends in Genetics
Volym
18
Issue
5
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Biological Sciences
Nyckelord
- bacteria
- plasmid
- riboregulator
- antisense RNA
- non-coding RNA
- gene silencing
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1362-4555