Urachal signet-cell adenocarcinoma

Summary, in English

This report presents two cases of urachal signet-cell adenocarcinoma (USCA). Two men, aged 53 and 51 years, presented with haematuria. Cystoscopy showed tumours in the dome of the bladder and transurethral resection revealed signet ring cell carcinoma. They both underwent cystoprostatectomy but died of metastatic disease after 14 and 26 months. USCA is a very rare tumour with poor prognosis. Only 25 cases have been reported. The tumours have a specific gross and microscopic morphology but must be distinguished from metastases of signet ring cell originating from other sites. Immunohistochemistry is helpful for the determination of the primary site.

• Författare: Lars Egevad; Ulf Håkansson; Magnus Grabe; Roy Ehrnström
• Avdelning/ar: Institutionen för kliniska vetenskaper, Malmö; Patologi, Malmö
• Publiceringsår: 2009
• Språk: Engelska
• Sidor: 88-91
• Publikation/Tidskrift/Serie: Scandinavian Journal of Urology and Nephrology
• Volym: 43
• Issue: 1
• Länkar: http://dx.doi.org/10.1080/00365590802361914
• Dokumenttyp: Artikel i tidskrift
• Förlag: Taylor & Francis
• Ämne: Cell and Molecular Biology; Urology and Nephrology; Cancer and Oncology
• Nyckelord: urachus; signet cell; pathology; Carcinoma; human; urinary bladder
• Status: Published
• Forskningsgrupp: Pathology, Malmö
• ISBN/ISSN/Övrigt: ISSN: 0036-5599