High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients

Summary, in English

UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.

METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.

RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.

CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.

• Författare: Johan Wassélius; Jonas Malmstedt; Bo Kalin; Stig Larsson; Anders Sundin; Ulf Hedin; Hans Jacobsson
• Publiceringsår: 2008-10
• Språk: Engelska
• Sidor: 5-1601
• Publikation/Tidskrift/Serie: Journal of Nuclear Medicine
• Volym: 49
• Issue: 10
• Länkar: http://dx.doi.org/10.2967/jnumed.108.053462
• Dokumenttyp: Artikel i tidskrift
• Förlag: Society of Nuclear Medicine
• Ämne: Radiology, Nuclear Medicine and Medical Imaging; Cardiac and Cardiovascular Systems
• Nyckelord: Aged; Aged, 80 and over; Aneurysm; Aorta; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis; Diagnostic Imaging; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Journal Article; Research Support, Non-U.S. Gov't
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0161-5505