Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial.
Författare
Summary, in English
Cholesterol lowering statins have been demonstrated to exert anti-tumoral effects on breast cancer by decreasing proliferation as measured by Ki67. The biological mechanisms behind the anti-proliferative effects remain elusive. The aim of this study was to investigate potential statin-induced effects on the central cell cycle regulators cyclin D1 and p27.
Avdelning/ar
- Bröstcancer - prevention & intervention
- Bröstcancer-genetik
- Tumörmikromiljö
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
Publiceringsår
2015
Språk
Engelska
Publikation/Tidskrift/Serie
Journal of Translational Medicine
Volym
13
Issue
133
Fulltext
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BioMed Central (BMC)
Ämne
- Cancer and Oncology
Status
Published
Forskningsgrupp
- Breast cancer prevention & intervention
ISBN/ISSN/Övrigt
- ISSN: 1479-5876