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Ethanol reduces rCBF activation of left dorsolateral prefrontal cortex during a verbal fluency task

In English

Författare

Summary, in English

Measurements of regional cerebral blood flow were made in 20 healthy young male subjects during sobriety and inebriation (0.06 % blood alcohol) during rest and during performance of a word fluency test. Word production was decreased during inebriation. The activation within the frontotemporal part of the left dorsolateral prefrontal cortex was preserved during intoxication. During inebriation no activation response to the word fluency test was seen in the anterior prefrontal part of the dorsolateral prefrontal cortex. This area showed a marked activation response during sobriety. Hemispheric function and specialization seems thus to be adversely affected by ethanol.

Publiceringsår

2001

Språk

Engelska

Sidor

197-215

Publikation/Tidskrift/Serie

Brain and Language

Volym

77

Issue

2

Dokumenttyp

Artikel i tidskrift

Förlag

Elsevier

Ämne

  • Psychology

Nyckelord

  • DLPFC
  • verbal fluency
  • cortical asymmetry
  • ethanol
  • functional lateralization
  • Key Words: regional cerebral blood flow

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1090-2155