Meny

Javascript verkar inte påslaget? - Vissa delar av Lunds universitets webbplats fungerar inte optimalt utan javascript, kontrollera din webbläsares inställningar.
Du är här

COMPRENDO: Focus and approach.

Författare:
  • U Schulte-Oehlmann
  • T Albanis
  • A Allera
  • J Bachmann
  • Pia Berntsson
  • N Beresford
  • DC Carnevali
  • F Ciceri
  • T Dagnac
  • J Falandysz
  • S Galassi
  • D Hala
  • G Janer
  • R Jeannot
  • S Jobling
  • I King
  • D Klingmüller
  • W Kloas
  • KO Kusk
  • R Levada
  • S Lo
  • I Lutz
  • J Oehlmann
  • Stina Oredsson
  • C Porte
  • M Rand-Weaver
  • V Sakkas
  • M Sugni
  • C Tyler
  • R van Aerle
  • C van Ballegoy
  • L Wollenberger
Publiceringsår: 2006
Språk: Engelska
Sidor: 98-100
Publikation/Tidskrift/Serie: Environ Health Perspect.
Volym: 114
Nummer: Supplement 1
Dokumenttyp: Artikel
Förlag: National Institute of Environmental Health Science

Sammanfattning

Tens of thousands of man-made chemicals are in regular use and discharged into the environment. Many of them are known to interfere with the hormonal systems in humans and wildlife. Given the complexity of endocrine systems, there are many ways in which endocrine-disrupting chemicals (EDCs) can affect the body's signaling system, and this makes unraveling the mechanisms of action of these chemicals difficult. A major concern is that some of these EDCs appear to be biologically active at extremely low concentrations. There is growing evidence to indicate that the guiding principle of traditional toxicology that "the dose makes the poison" may not always be the case because some EDCs do not induce the classical dose-response relationships. The European Union project COMPRENDO (Comparative Research on Endocrine Disrupters--Phylogenetic Approach and Common Principles focussing on Androgenic/Antiandrogenic Compounds) therefore aims to develop an understanding of potential health problems posed by androgenic and antiandrogenic compounds (AACs) to wildlife and humans by focusing on the commonalities and differences in responses to AACs across the animal kingdom (from invertebrates to vertebrates) .

Disputation

Nyckelord

  • Biology and Life Sciences
  • phylogenetic approach
  • wildlife exposure.
  • molecular screening
  • environmental health
  • antiandrogens
  • androgens
  • endocrine disruptor

Övriga

Published
Yes
  • ISSN: 0091-6765

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
Om webbplatsen