Expression of cyclin d1 and its association with disease characteristics in bladder cancer.

Summary, in English

Aim: Invasive urothelial carcinoma of the bladder (UCB) is characterized by alterations in cell-cycle regulatory pathways. Defects in the expression of cyclin D1, a key cell-cycle regulator, have been implicated in progression of various types of cancer. In the present study, we investigated whether cyclin D1 expression is associated with clinicopathological parameters and whether it has any potential prognostic value in determining risk of UCB recurrence.

• Författare: Pradeep Kopparapu; Stephen A Boorjian; Brian D Robinson; Martin Downes; Lorraine J Gudas; Nigel Mongan; Jenny L Persson
• Avdelning/ar: Experimentell cancerforskning, Malmö; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 5235-5242
• Publikation/Tidskrift/Serie: Anticancer research
• Volym: 33
• Issue: 12
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/24324055?dopt=Abstract
• Dokumenttyp: Artikel i tidskrift
• Förlag: International Institute of Cancer Research
• Ämne: Cancer and Oncology
• Status: Published
• Forskningsgrupp: Experimental Cancer Research, Malmö
• ISBN/ISSN/Övrigt: ISSN: 1791-7530