Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.
Författare
Summary, in English
Airway hyperresponsiveness (AHR) to inhaled mannitol is associated with indirect markers of mast cell activation and eosinophilic airway inflammation. It is unknown how AHR to mannitol relates to mast cell phenotype, mast cell function and measures of eosinophilic inflammation in airway tissue. We compared the number and phenotype of mast cells, mRNA expression of mast cell associated genes and number of eosinophils in airway tissue of subjects with asthma and healthy controls in relation to AHR to mannitol.
Avdelning/ar
Publiceringsår
2016
Språk
Engelska
Sidor
288-297
Publikation/Tidskrift/Serie
Clinical and Experimental Allergy
Volym
46
Issue
2
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley
Ämne
- Respiratory Medicine and Allergy
Status
Published
Forskningsgrupp
- Airway Inflammation and Immunology
ISBN/ISSN/Övrigt
- ISSN: 1365-2222