Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.

Summary, in English

Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.

• Författare: Martin Wahlestedt; David Bryder
• Avdelning/ar: Institutionen för experimentell medicinsk vetenskap; StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 555-556
• Publikation/Tidskrift/Serie: Cell Stem Cell
• Volym: 14
• Issue: 5
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/24792111?dopt=Abstract; http://dx.doi.org/10.1016/j.stem.2014.04.008
• Dokumenttyp: Artikel i tidskrift
• Förlag: Cell Press
• Ämne: Cell Biology
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1934-5909