The clinical significance of BRAF and NRAS mutations in a clinic-based metastatic melanoma cohort.

Summary, in English

BRAF and NRAS mutations are frequently found in melanoma tumours and recently developed BRAF targeted therapies demonstrate significant clinical benefit.

• Författare: Henrik Ekedahl; Helena Cirenajwis; Katja Harbst; Ana Carneiro; Kari Nielsen; Håkan Olsson; L Lundgren; Christian Ingvar; Gunilla Jönsson
• Avdelning/ar: Bröstcancer-genetik; Kirurgi, Lund; Dermatologi och venereologi, Lund; Cellpatologi, Malmö; Melanoma Genomics; EpiHealth: Epidemiology for Health; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 1049-1055
• Publikation/Tidskrift/Serie: British Journal of Dermatology
• Volym: 169
• Issue: 5
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/23855428?dopt=Abstract; http://dx.doi.org/10.1111/bjd.12504
• Dokumenttyp: Artikel i tidskrift
• Förlag: Wiley-Blackwell
• Ämne: Dermatology and Venereal Diseases
• Status: Published
• Forskningsgrupp: Cell Pathology, Malmö; Melanoma Genomics
• ISBN/ISSN/Övrigt: ISSN: 1365-2133