Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
Författare
Summary, in English
Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound preventing S100A9 binding to TLR-4. We investigated the effect of paquinimod on experimental OA and human OA synovium.
Avdelning/ar
- Immunology
Publiceringsår
2015
Språk
Engelska
Sidor
2254-2258
Publikation/Tidskrift/Serie
Annals of the Rheumatic Diseases
Volym
74
Issue
12
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BMJ Publishing Group
Ämne
- Rheumatology and Autoimmunity
Status
Published
Forskningsgrupp
- Immunology
ISBN/ISSN/Övrigt
- ISSN: 1468-2060