Combined Androgen and Estrogen Receptor Status in Breast Cancer: Treatment Prediction and Prognosis in a Population-based Prospective Cohort.

Summary, in English

To evaluate whether tumor androgen receptor (AR) expression was prognostic and/or predictive for endocrine treatment alone or in combination with estrogen receptor (ER). The AR has been hypothesized to have differential prognostic roles in breast cancer depending on tumor ER-status, and to influence endocrine treatment response.

• Författare: Karin Elebro; Signe Borgquist; Maria Simonsson; Andrea Markkula; Karin Jirström; Christian Ingvar; Carsten Rose; Helena Jernström
• Avdelning/ar: Epidemiologi och farmakogenetik; Bröstcancer - prevention & intervention; Bröstcancer-genetik; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation; Tumörmikromiljö; Kirurgi, Lund
• Publiceringsår: 2015
• Språk: Engelska
• Sidor: 3640-3650
• Publikation/Tidskrift/Serie: Clinical Cancer Research
• Volym: 21
• Issue: 16
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/25904752?dopt=Abstract; http://dx.doi.org/10.1158/1078-0432.CCR-14-2564
• Dokumenttyp: Artikel i tidskrift
• Förlag: American Association for Cancer Research
• Ämne: Cancer and Oncology
• Status: Published
• Forskningsgrupp: Epidemiology and pharmacogenetics; Breast cancer prevention & intervention
• ISBN/ISSN/Övrigt: ISSN: 1078-0432