Expression of VEGF and Its receptors VEGFR1/VEGFR2 Is Associated with Invasiveness of Bladder Cancer.

Summary, in English

Aim: Vascular endothelial growth factor (VEGF) signaling is frequently altered in invasive tumor cells and is associated with patient outcome. In the present study, we examined VEGF, VEGFR1, and VEGFR2 expression in non-muscle invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MIBC), and evaluated the association between VEGF and its receptors with disease characteristics and bladder cancer recurrence.

• Författare: Pradeep Kumar Kopparapu; Stephen A Boorjian; Brian D Robinson; Martin Downes; Lorraine J Gudas; Nigel Mongan; Jenny L Persson
• Avdelning/ar: Experimentell cancerforskning, Malmö; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 2381-2390
• Publikation/Tidskrift/Serie: Anticancer research
• Volym: 33
• Issue: 6
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/23749886?dopt=Abstract
• Dokumenttyp: Artikel i tidskrift
• Förlag: International Institute of Cancer Research
• Ämne: Cancer and Oncology
• Status: Published
• Forskningsgrupp: Experimental Cancer Research, Malmö
• ISBN/ISSN/Övrigt: ISSN: 1791-7530