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Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?

Författare:
Publiceringsår: 2012
Språk: Engelska
Sidor: 343-345
Publikation/Tidskrift/Serie: Proteomics Clinical Applications
Volym: 6
Nummer: 7-8
Dokumenttyp: Artikel i tidskrift
Förlag: John Wiley & Sons

Sammanfattning

Proteomics has not delivered biomarkers of clinical value, despite massive efforts. The technologies that are emerging today have, however, the power to reach deep into proteomes and to identify patterns associated with different diseases. The study design is then crucial and sample quality, bioinformatic approaches, pre-validation, using independent patient cohort, need to attract increased attention before proteomics will contribute to the needs of personalized medicine.

Nyckelord

  • Cell and Molecular Biology
  • over-fitting
  • biobanks
  • pre-validation
  • bioinformatics
  • Signatures

Övriga

Published
  • ISSN: 1862-8354

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