Chlorhexidine for prevention of neonatal colonization with group B streptococci. III. Effect of vaginal washing with chlorhexidine before rupture of the membranes
Författare
Summary, in English
A single vaginal washing with 2 g/l of chlorhexidine was performed before rupture of the membranes in 19 parturients who were urogenital carriers of group B streptococci (GBS). Two (11%) of the infants became colonized immediately after birth, in contrast to 16 of 41 (39%) infants to controls (P = 0.02). A significant reduction of GBS colonization of the ear (P = 0.02) and umbilicus (P = 0.01) was noted. Taken together, 2 of 57 (4%) cultures obtained at birth were positive in the chlorhexidine group, in contrast to 30 of 123 (24%) among the controls (P less than 0.01). These findings raise hope for the design of a simple washing procedure which might prevent serious infections in the early neonatal period with GBS but also with other chlorhexidine-sensitive organisms.
Avdelning/ar
Publiceringsår
1985
Språk
Engelska
Sidor
231-236
Publikation/Tidskrift/Serie
European Journal of Obstetrics, Gynecology, and Reproductive Biology
Volym
19
Issue
4
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Obstetrics, Gynecology and Reproductive Medicine
Nyckelord
- neonatal colonization
- group B streptococci
- chlorhexidine
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0301-2115