Biologically active secondary metabolites from the ascomycete A111-95 - 1. Production, isolation and biological activities
Författare
Summary, in English
Eight secondary metabolites were isolated from submerged cultures of the ascomycete A111-95 during a search for new nematicidal metabolites. (-)-Galiellalactone (7) and compound 2 are metabolites previously obtained from cultures of Galiella rufa while the compounds 1, 3, 4, 5, 6 and 8 (3 and 4 were obtained as an unseparable mixture), were isolated as natural products for the first time. Compound 2, pregaliellalactone (5) and the mixture of 3 and 4 showed nematicidal activities towards Caenorhabditis elegans and Meloidogyne incognita. All compounds showed moderate or weak cytotoxic activities.
Avdelning/ar
Publiceringsår
2002
Språk
Engelska
Sidor
36-40
Publikation/Tidskrift/Serie
Journal of Antibiotics
Volym
55
Issue
1
Dokumenttyp
Artikel i tidskrift
Förlag
Japan Antibiotics Research Association
Ämne
- Organic Chemistry
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0021-8820