An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction.

• Författare: Mikael Adner; Andrew C Rose; Yaping Zhang; Karl Swärd; Mikael Benson; Rolf Uddman; Nigel P Shankley; Lars-Olaf Cardell
• Avdelning/ar: Clinical and Experimental Allergy Research; Cellulär biomekanik
• Publiceringsår: 2002
• Språk: Engelska
• Sidor: 971-982
• Publikation/Tidskrift/Serie: British Journal of Pharmacology
• Volym: 137
• Issue: 7
• Länkar: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12429569&dopt=Abstract; http://dx.doi.org/10.1038/sj.bjp.0704928
• Dokumenttyp: Artikel i tidskrift
• Förlag: Wiley
• Ämne: Pharmacology and Toxicology
• Nyckelord: Dose-Response Relationship; Carbachol: pharmacology; Gene Expression Profiling; Inflammation Mediators: pharmacology; Drug; Muscle; Animal; Muscle Contraction: drug effects; Muscarinic Antagonists: pharmacology; Inbred BALB C; Smooth: drug effects; Receptors; Potassium Chloride: pharmacology; Oligonucleotide Array Sequence Analysis; Organ Culture; Smooth: physiology; Tumor Necrosis Factor: pharmacology; Trachea: physiology; Trachea: metabolism; Non-U.S. Gov't; Trachea: drug effects; Time Factors; Serotonin: drug effects; Support; Serotonin Antagonists: pharmacology; Serotonin Agonists: pharmacology; Serotonin Agents: pharmacology; Serotonin: physiology; Serotonin: pharmacology; Male; Isoproterenol: pharmacology; Mice; Atropine: pharmacology
• Status: Published
• Forskningsgrupp: Clinical and Experimental Allergy Research; Cellular Biomechanics
• ISBN/ISSN/Övrigt: ISSN: 1476-5381