Myeloid-related protein 14 promote inflammation and injury in meningitis.
Författare
Summary, in English
Neutrophilic inflammation often persists over days despite efficient antibiotic treatment and contributes to brain damage in bacterial meningitis. We proposed here that MRP14, an abundant cytosolic protein in myeloid cells, acts as an endogenous danger signal, driving inflammation and aggravating tissue injury.
Avdelning/ar
- Immunology
Publiceringsår
2015
Språk
Engelska
Sidor
247-257
Publikation/Tidskrift/Serie
Journal of Infectious Diseases
Volym
212
Issue
2
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Oxford University Press
Ämne
- Infectious Medicine
Status
Published
Forskningsgrupp
- Immunology
ISBN/ISSN/Övrigt
- ISSN: 1537-6613