The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.
Författare
Summary, in English
The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood.
Avdelning/ar
- Undersökning av molekylära sjukdomsmekanismer vid blodcancer
- Avdelningen för hematologi och transfusionsmedicin
- Molekylär neurogenetik
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
Publiceringsår
2014
Språk
Engelska
Publikation/Tidskrift/Serie
Molecular Cancer
Volym
13
Fulltext
- Available as PDF - 866 kB
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Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BioMed Central (BMC)
Ämne
- Cancer and Oncology
Status
Published
Forskningsgrupp
- Transcriptional mechanisms for the Wilms’ tumor gene 1 (WT1) oncoprotein
- Molecular Neurogenetics
ISBN/ISSN/Övrigt
- ISSN: 1476-4598