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Airway epithelial repair: breathtakingly quick and multipotentially pathogenic

In English

Författare

Summary, in English

Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.

Publiceringsår

1997

Språk

Engelska

Sidor

1010-1012

Publikation/Tidskrift/Serie

Thorax

Volym

52

Issue

11

Dokumenttyp

Artikel i tidskrift

Förlag

BMJ Publishing Group

Ämne

  • Respiratory Medicine and Allergy

Nyckelord

  • asthma pathology
  • mucosal barrier
  • epithelial repair

Status

Published

Forskningsgrupp

  • Airway Inflammation and Immunology

ISBN/ISSN/Övrigt

  • ISSN: 1468-3296