Caffeine and caffeic acid inhibit growth and modify estrogen receptor (ER) and insulin-like growth factor I receptor (IGF-IR) levels in human breast cancer.

Summary, in English

Epidemiological studies indicate that dietary factors, such as coffee, may influence breast cancer and modulate hormone receptor status. The purpose of this translational study was to investigate how coffee may impact on breast cancer growth in relation to estrogen receptor-α (ER) status.

• Författare: Ann Rosendahl; Claire M Perks; Li Zeng; Andrea Markkula; Maria Simonsson; Carsten Rose; Christian Ingvar; Jeff Mp Holly; Helena Jernström
• Avdelning/ar: Epidemiologi och farmakogenetik; Bröstcancer-genetik; Kirurgi, Lund; Tumörmikromiljö; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2015
• Språk: Engelska
• Sidor: 1877-1887
• Publikation/Tidskrift/Serie: Clinical Cancer Research
• Volym: 21
• Issue: 8
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/25691730?dopt=Abstract; http://dx.doi.org/10.1158/1078-0432.CCR-14-1748
• Dokumenttyp: Artikel i tidskrift
• Förlag: American Association for Cancer Research
• Ämne: Cancer and Oncology
• Status: Published
• Forskningsgrupp: Epidemiology and pharmacogenetics
• ISBN/ISSN/Övrigt: ISSN: 1078-0432